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If necessary, N-terminal pyroglutamate is enzymatically removed prior to gas phase sequencing. Journal of Multidisciplinary Healthcare ; In the same period, the average number of biologics doubled to seven biologic license applications BLA per year. The ongoing clinical trial is planning to start pact testing. Hubert C.
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In addition, due to the very specific nature of epigenetic biomarkers, these technologies may enable the identification of ctDNA tissue-of-origin as well as the stage of disease. Maand Januari Februari Maart April Mei Juni Juli Augustus September Oktober November December Dag 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 Jaar
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As these epigenetic changes are stable, they can be mapped and measured from clinical samples, providing powerful biomarkers for disease12—
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- Since leucine and isoleucine have different structures and hence retention times, they can readily be distinguished from one another Figure 2.
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